Continuing Education credit registration fee of $7 to obtain the certificate. Virtual: https://events.vtools.ieee.org/m/493913

Histotripsy is a method of non-invasive ultrasonic surgery using very intense pulses of focused ultrasound to mechanically fracture tissue. As of July 2025, histotripsy systems have been installed at more than 50 medical centers worldwide for ablation of liver tumors. This talk summarizes the approximately 25 year process of translating the physical mechanism of ultrasonically generated cavitation to a clinical product. I will also highlight a number of the substantial challenges faced by academics attempting to pursue scientific research translation, a large number of mistakes, and a few lucky breaks that lead to our success. This presentation is a virtual event hosted by the Engineering Medicine and Biology Chapter of SE Michigan IEEE Section Speaker(s): Timothy Hall, Virtual: https://events.vtools.ieee.org/m/515293